RHD: Alleles by mutation in exon 2

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exon 2
Position	Substitution	Effect	Templated	Alleles
25284573	149	149T>A	V50D		RHD(V50D)
25284574	150	150T>C		X	DAR(CE2:V50V-S68N) DHAR DIII type 7 DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D DIIIa150C DKK RHCE(1-3)-RHD(4-10) RHCE(1-9)-RHD DAU-0.2 DIIIb (Caucasian) RHD-RHCE(2)-RHD(F355S) RHD-RHCE(2-10) RHD-RHCE(2-5)-RHD RHD-ceAG.05(2)-D
25284577	153	153C>T	p.Gly51Gly
25284581	157	157G>T	D53Y		RHD(D53Y)
25284584	160	160C>T	p.Leu54Leu
25284585	161	161T>C	L54P		DMH
25284586	162	162G>C	p.Leu54Leu
25284587	163	163A>C	T55P		weak D type 130
25284589	165	165C>T			RHD(165C>T) weak D type 68
25284590	166	166G>A	V56M		RHD(V56M,W90X)
25284590	166	166G>C	p.Val56Leu
25284597	173	173C>T	A58V		weak D type 143
25284598	174	174G>A	p.Ala58Ala
25284599	175	175G>A	A59T		weak D type 151
25284600	176	176C>A	A59D		weak D type 121
25284600	176	176C>T	p.Ala59Val
25284602	178	178A>C	I60L	X	DAR(CE2:V50V-S68N) DHAR DIII type 7 DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D DKK RHCE(1-3)-RHD(4-10) RHCE(1-9)-RHD RHD(60L,S230I) RHD(I60L) RHD(I60L,N152T,T201R,F223V,G263R) weak D type 3.1 DIIIb (Caucasian) RHD-RHCE(2)-RHD(F355S) RHD-RHCE(2-10) RHD-RHCE(2-5)-RHD RHD-ceAG.05(2)-D weak D type 29 RHD(I60L,S68N,K198N,F223V,G314V,I342T)
25284602	178	178A>G	I60V		RHD(I60V,S103P,F161S,L214F)
25284603	179	179T>C	p.Ile60Thr
25284606	182	182G>C	G61A		weak D type 88
25284606	182	182G>T	G61V		weak D type 48
25284610	186	186G>T	L62F		Ccdes-1 D-SPM D186T DIII type 4 DIII type 4.2 DIII type 5 DIII type 9 DIIIa150C DIV(S103P) DIV-DOL DIV type 1.1 DIV type 1.0 DIVa-like
25284611	187	187G>T	G63C		weak D type 152
25284612	188	188G>T	p.Gly63Val
25284616	192	192C>G	p.Phe64Leu
25284620	196	196A>T	p.Thr66Ser
25284624	200	200C>A	p.Ser67Ter
25284624	200	200C>G	S67W		weak D type 105
25284625	201	201G>A		X	DAR(CE2:V50V-S68N) DHAR DIII type 7 DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D DKK RHCE(1-3)-RHD(4-10) RHCE(1-9)-RHD DAU-14 DIIIb (Caucasian) RHD-RHCE(2)-RHD(F355S) RHD-RHCE(2-10) RHD-RHCE(2-5)-RHD RHD-ceAG.05(2)-D weak D type 29 RHD(I60L,S68N,K198N,F223V,G314V,I342T)
25284627	203	203G>A	S68N	X	DAR(CE2:V50V-S68N) DHAR DIII type 7 DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D DKK RHCE(1-3)-RHD(4-10) RHCE(1-9)-RHD DAU-14 DIIIb (Caucasian) RHD-RHCE(2)-RHD(F355S) RHD-RHCE(2-10) RHD-RHCE(2-5)-RHD RHD-ceAG.05(2)-D weak D type 29 RHD(I60L,S68N,K198N,F223V,G314V,I342T)
25284627	203	203G>C	S68T		RHD(S68T)-RHCe(3-9)-RHD weak D type 74
25284632	208	208C>T	R70W		weak D type 122 weak D type 45.2
25284632	208	208del insTG			RHD(208delinsTG)
25284633	209	209G>A	R70Q		DAU-2 weak D type 85
25284637	213	213A>T	R71S		RHD(R71S)
25284639	215	215AC>CA	72H>P		RHD(H72P,S73C)
25284639	215	215A>G	p.His72Arg
25284640	216	216dupCA			RHD(216dupCA,1195G>A)
25284641	217	217A>G	p.Ser73Gly
25284641	217	217A>T	S73C		RHD(H72P,S73C)
25284644	220	220T>G	W74G		weak D type 106
25284645	221	221G>A	p.Trp74Ter
25284647	223	223A>G	p.Ser75Gly
25284647	223	223A>T	S75C		weak D type 107
25284649	225	225C>T	p.Ser75Ser
25284651	227	227G>A	S76N		weak D type 84
25284652	228	228T>C	p.Ser76Ser
25284656	232	232G>A	p.Ala78Thr
25284657	233	233C>T	p.Ala78Val
25284662	238	238A>G	p.Asn80Asp
25284663	239	239A>G	p.Asn80Ser
25284664	240	240C>T	p.Asn80Asn
25284665	241	241C>T	p.Leu81Phe
25284666	242	242T>C	L81P		RHD(L81P)
25284675	251	251T>C	L84P		RHD(L84P) RHD(M1I,L84P)
25284677	253	253G>C	p.Ala85Pro
25284678	254	254C>G	A85G		weak D type 131 RHD-ceAG.05(2)-D
25284678	254	254C>T	A85V		DAU-11
25284679	255	255G>A	A85A		RHD(255G>A, 1227G>A,)
25284684	260	260G>A	G87D		weak D type 35
25284690	266	266A>C	p.Gln89Pro
25284690	266	266A>G	Q89R		RHD(Q89R)
25284694	270	270G>A	W90X		RHD(V56M,W90X) RHD(W90X)
25284694	270	270G>C	p.Trp90Cys
25284700	276	276del C	p.Leu93CysfsTer6
25284701	277	277C>T	p.Leu93Leu
25284702	278	278T>G	L93R		RHD(L93R)
25284708	284	284A>G	D95G		RHD(D95G)
25284709	285	285C>T	p.Asp95Asp
25284710	286	286G>A	G96S		RHD(G96S)
25284710	286	286G>C	G96R		RHD(G96R)
25284711	287	287G>A	G96D		RHD(G96D)
25284715	291	291C>T	p.Phe97Phe
25284721	297	297del 23			RHD(297del23)
25284724	300	300G>A	p.Gln100Gln
25284725	301	301T>A	F101I		weak D type 2.1
25284731	307	307T>C	S103P	X	DHAR DIII type 4.2 DIII type 7 DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D DIV(S103P) DKK DVII type 2 RHCE(1-3)-RHD(4-10) RHCE(1-9)-RHD RHD(I60V,S103P,F161S,L214F) RHD(S103P) DIIIb (Caucasian) RHD-RHCE(2)-RHD(F355S) RHD-RHCE(2-10) RHD-RHCE(2-5)-RHD RHD-ceAG.05(2)-D
25284735	311	311G>C	p.Gly104Ala
25284740	316	316G>A	p.Val106Met
25284746	322	322A>G	p.Ile108Val
25284749	325	325A>G	p.Thr109Ala
25284749	325	325del A			RHD(325delA)
25284750	326	326C>T	p.Thr109Ile
25284751	327	327327_487-4164dup			weak D type 150
25284752	328	328C>A	p.Leu110Met
25284753	329	329T>C	L110P		DVII DVII type 2 RHD(L110P)-CE(3-9)-D
25284753	329	329del TG	p.Phe111GlnfsTer48
25284754	330	330G>A	p.Leu110Leu
25284754	330	330del GT			RHD(330delGT)
25284757	333	333C>T	p.Phe111Phe
25284758	334	334A>G	S112G		RHD(S112G)
25284759	335	335G>C	S112T		RHD(S112T)
25284759	335	335G>T	S112I		RHD(S112I)